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Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia

Transient receptor potential vanilloid 1 (TRPV1) plays a major role in hyperalgesia and allodynia and is expressed both in the peripheral and central nervous systems (CNS). However, few studies have evaluated mechanisms by which CNS TRPV1 mediates hyperalgesia and allodynia after injury. We hypothes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Patwardhan, Amol M., Scotland, Phoebe E., Akopian, Armen N., Hargreaves, Kenneth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764734/
https://ncbi.nlm.nih.gov/pubmed/19843694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905415106
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