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Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia

Transient receptor potential vanilloid 1 (TRPV1) plays a major role in hyperalgesia and allodynia and is expressed both in the peripheral and central nervous systems (CNS). However, few studies have evaluated mechanisms by which CNS TRPV1 mediates hyperalgesia and allodynia after injury. We hypothes...

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Detalhes bibliográficos
Main Authors: Patwardhan, Amol M., Scotland, Phoebe E., Akopian, Armen N., Hargreaves, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764734/
https://ncbi.nlm.nih.gov/pubmed/19843694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905415106
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