A-Kinase Anchoring Protein Mediates TRPV1 Thermal Hyperalgesia through PKA Phosphorylation of TRPV1

Certain phosphorylation events are tightly controlled by scaffolding proteins such as A-Kinase Anchoring Protein (AKAP). On nociceptive terminals, phosphorylation of transient receptor potential channel type 1 (TRPV1) results in the sensitization to many different stimuli, contributing to the develo...

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Detalhes bibliográficos
Main Authors: Jeske, Nathaniel A., Diogenes, Anibal, Ruparel, Nikita B., Fehrenbacher, Jill C., Henry, Michael, Akopian, Armen N., Hargreaves, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593399/
https://ncbi.nlm.nih.gov/pubmed/18381233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.02.022
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