Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease

Mutations in a variety of myofibrillar genes cause dilated cardiomyopathy (DCM) in humans, usually with dominant inheritance and incomplete penetrance. Here, we sought to clarify the functional effects of the previously identified DCM-causing TTN 2-bp insertion mutation (c.43628insAT) and generated...

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Detalhes bibliográficos
Main Authors: Gramlich, Michael, Michely, Beate, Krohne, Christian, Heuser, Arnd, Erdmann, Bettina, Klaassen, Sabine, Hudson, Bryan, Magarin, Manuela, Kirchner, Florian, Todiras, Mihail, Granzier, Henk, Labeit, Siegfried, Thierfelder, Ludwig, Gerull, Brenda
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764556/
https://ncbi.nlm.nih.gov/pubmed/19406126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.04.014
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