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Complex architecture and regulated expression of the Sox2ot locus during vertebrate development

The Sox2 gene is a key regulator of pluripotency embedded within an intron of a long noncoding RNA (ncRNA), termed Sox2 overlapping transcript (Sox2ot), which is transcribed in the same orientation. However, this ncRNA remains uncharacterized. Here we show that Sox2ot has multiple transcription star...

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Detalhes bibliográficos
Main Authors: Amaral, Paulo P., Neyt, Christine, Wilkins, Simon J., Askarian-Amiri, Marjan E., Sunkin, Susan M., Perkins, Andrew C., Mattick, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764477/
https://ncbi.nlm.nih.gov/pubmed/19767420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1705309
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