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Complex architecture and regulated expression of the Sox2ot locus during vertebrate development

The Sox2 gene is a key regulator of pluripotency embedded within an intron of a long noncoding RNA (ncRNA), termed Sox2 overlapping transcript (Sox2ot), which is transcribed in the same orientation. However, this ncRNA remains uncharacterized. Here we show that Sox2ot has multiple transcription star...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Amaral, Paulo P., Neyt, Christine, Wilkins, Simon J., Askarian-Amiri, Marjan E., Sunkin, Susan M., Perkins, Andrew C., Mattick, John S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764477/
https://ncbi.nlm.nih.gov/pubmed/19767420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1705309
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