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Allele-specific repression of Sox2 through the long non-coding RNA Sox2ot
The transcription factor Sox2 controls the fate of pluripotent stem cells and neural stem cells. This gatekeeper function requires well-regulated Sox2 levels. We postulated that Sox2 regulation is partially controlled by the Sox2 overlapping long non-coding RNA (lncRNA) gene Sox2ot. Here we show tha...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5762901/ https://ncbi.nlm.nih.gov/pubmed/29321583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18649-4 |
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