Sequence variant (CTAGGG)(n) in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad

Short contiguous arrays of variant CTAGGG repeats in the human telomere are unstable in the male germline and somatic cells, suggesting formation of unusual structures by this repeat type. Here, we report on the structure of an intramolecular G-quadruplex formed by DNA sequences containing four huma...

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Bibliographic Details
Main Authors: Lim, Kah Wai, Alberti, Patrizia, Guédin, Aurore, Lacroix, Laurent, Riou, Jean-François, Royle, Nicola J., Mergny, Jean-Louis, Phan, Anh Tuân
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764449/
https://ncbi.nlm.nih.gov/pubmed/19692585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp630
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