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Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G·G·X·O tetrad
G-quadruplexes are four-stranded structures built from stacked G-tetrads (G·G·G·G), which are planar cyclical assemblies of four guanine bases interacting through Hoogsteen hydrogen bonds. A G-quadruplex containing a single guanine analog substitution, such as 8-oxoguanine (O) or xanthine (X), would...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666386/ https://ncbi.nlm.nih.gov/pubmed/26400177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv826 |
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