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Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G·G·X·O tetrad

G-quadruplexes are four-stranded structures built from stacked G-tetrads (G·G·G·G), which are planar cyclical assemblies of four guanine bases interacting through Hoogsteen hydrogen bonds. A G-quadruplex containing a single guanine analog substitution, such as 8-oxoguanine (O) or xanthine (X), would...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Cheong, Vee Vee, Heddi, Brahim, Lech, Christopher Jacques, Phan, Anh Tuân
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666386/
https://ncbi.nlm.nih.gov/pubmed/26400177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv826
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