Sequence variant (CTAGGG)(n) in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad

Short contiguous arrays of variant CTAGGG repeats in the human telomere are unstable in the male germline and somatic cells, suggesting formation of unusual structures by this repeat type. Here, we report on the structure of an intramolecular G-quadruplex formed by DNA sequences containing four huma...

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Main Authors: Lim, Kah Wai, Alberti, Patrizia, Guédin, Aurore, Lacroix, Laurent, Riou, Jean-François, Royle, Nicola J., Mergny, Jean-Louis, Phan, Anh Tuân
格式: Artigo
語言:Inglês
出版: Oxford University Press 2009
主題:
Structural Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764449/
https://ncbi.nlm.nih.gov/pubmed/19692585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp630
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