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Sequence variant (CTAGGG)(n) in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad

Short contiguous arrays of variant CTAGGG repeats in the human telomere are unstable in the male germline and somatic cells, suggesting formation of unusual structures by this repeat type. Here, we report on the structure of an intramolecular G-quadruplex formed by DNA sequences containing four huma...

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Detalhes bibliográficos
Main Authors: Lim, Kah Wai, Alberti, Patrizia, Guédin, Aurore, Lacroix, Laurent, Riou, Jean-François, Royle, Nicola J., Mergny, Jean-Louis, Phan, Anh Tuân
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764449/
https://ncbi.nlm.nih.gov/pubmed/19692585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp630
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