Sequence variant (CTAGGG)(n) in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad

Short contiguous arrays of variant CTAGGG repeats in the human telomere are unstable in the male germline and somatic cells, suggesting formation of unusual structures by this repeat type. Here, we report on the structure of an intramolecular G-quadruplex formed by DNA sequences containing four huma...

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Detaylı Bibliyografya
Asıl Yazarlar: Lim, Kah Wai, Alberti, Patrizia, Guédin, Aurore, Lacroix, Laurent, Riou, Jean-François, Royle, Nicola J., Mergny, Jean-Louis, Phan, Anh Tuân
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Structural Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764449/
https://ncbi.nlm.nih.gov/pubmed/19692585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp630
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