Factor Xa Binding to Phosphatidylserine-Containing Membranes Produces an Inactive Membrane-Bound Dimer

Factor Xa (FXa) has a prominent role in amplifying both inflammation and the coagulation cascade. In the coagulation cascade, its main role is catalyzing the proteolytic activation of prothrombin to thrombin. Efficient proteolysis is well known to require phosphatidylserine (PS)-containing membranes...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Koklic, Tilen, Majumder, Rinku, Weinreb, Gabriel E., Lentz, Barry R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2009
Gaiak:
Membrane
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764068/
https://ncbi.nlm.nih.gov/pubmed/19843455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.043
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