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Phosphatidylserine and phosphatidylethanolamine regulate the structure and function of FVIIa and its interaction with soluble tissue factor

Cell membranes have important functions in many steps of the blood coagulation cascade, including the activation of factor X (FX) by the factor VIIa (FVIIa)-tissue factor (TF) complex (extrinsic X(ase)). FVIIa shares structural similarity with factor IXa (FIXa) and FXa. FIXa and FXa are regulated by...

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Bibliografiske detaljer
Udgivet i:Biosci Rep
Main Authors: Sengupta, Tanusree, Koklic, Tilen, Lentz, Barry R., Majumder, Rinku
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859323/
https://ncbi.nlm.nih.gov/pubmed/33479740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20204077
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