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Factor Xa Binding to Phosphatidylserine-Containing Membranes Produces an Inactive Membrane-Bound Dimer

Factor Xa (FXa) has a prominent role in amplifying both inflammation and the coagulation cascade. In the coagulation cascade, its main role is catalyzing the proteolytic activation of prothrombin to thrombin. Efficient proteolysis is well known to require phosphatidylserine (PS)-containing membranes...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Koklic, Tilen, Majumder, Rinku, Weinreb, Gabriel E., Lentz, Barry R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Biophysical Society 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764068/
https://ncbi.nlm.nih.gov/pubmed/19843455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.043
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