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Decreased CSF Aβ42 correlates with brain atrophy in cognitively normal elderly

OBJECTIVES: In order for therapies for Alzheimer's disease (AD) to have the greatest impact, it will likely be necessary to treat individuals in the “preclinical” (presymptomatic) stage. Fluid and neuroimaging measures are being explored as possible biomarkers of AD pathology that could aid in...

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Autores principales: Fagan, Anne M., Head, Denise, Shah, Aarti R., Marcus, Daniel, Mintun, Mark, Morris, John C., Holtzman, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763631/
https://ncbi.nlm.nih.gov/pubmed/19260027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21559
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