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Decreased CSF Aβ42 correlates with brain atrophy in cognitively normal elderly

OBJECTIVES: In order for therapies for Alzheimer's disease (AD) to have the greatest impact, it will likely be necessary to treat individuals in the “preclinical” (presymptomatic) stage. Fluid and neuroimaging measures are being explored as possible biomarkers of AD pathology that could aid in...

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Detalhes bibliográficos
Main Authors: Fagan, Anne M., Head, Denise, Shah, Aarti R., Marcus, Daniel, Mintun, Mark, Morris, John C., Holtzman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763631/
https://ncbi.nlm.nih.gov/pubmed/19260027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21559
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