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Decreased CSF Aβ42 correlates with brain atrophy in cognitively normal elderly

OBJECTIVES: In order for therapies for Alzheimer's disease (AD) to have the greatest impact, it will likely be necessary to treat individuals in the “preclinical” (presymptomatic) stage. Fluid and neuroimaging measures are being explored as possible biomarkers of AD pathology that could aid in...

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Autors principals: Fagan, Anne M., Head, Denise, Shah, Aarti R., Marcus, Daniel, Mintun, Mark, Morris, John C., Holtzman, David M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763631/
https://ncbi.nlm.nih.gov/pubmed/19260027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21559
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