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Amyloid Plaques Disrupt Resting State Default Mode Network Connectivity in Cognitively Normal Elderly
BACKGROUND: Important functional connections within the “default mode network” (DMN) are disrupted in Alzheimer’s disease (AD), likely from amyloid-beta (Aβ) plaque-associated neuronal toxicity. Here we sought to determine if pathological effects of Aβ amyloid plaques could be seen even in the absen...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829379/ https://ncbi.nlm.nih.gov/pubmed/19833321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.08.024 |
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