Amyloid Plaques Disrupt Resting State Default Mode Network Connectivity in Cognitively Normal Elderly

BACKGROUND: Important functional connections within the “default mode network” (DMN) are disrupted in Alzheimer’s disease (AD), likely from amyloid-beta (Aβ) plaque-associated neuronal toxicity. Here we sought to determine if pathological effects of Aβ amyloid plaques could be seen even in the absen...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Sheline, Yvette I., Raichle, Marcus E., Snyder, Abraham Z., Morris, John C., Head, Denise, Wang, Suzhi, Mintun, Mark A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829379/
https://ncbi.nlm.nih.gov/pubmed/19833321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.08.024
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi