RNA Dimerization Promotes PKR Dimerization and Activation

The double-stranded RNA (dsRNA)-activated protein kinase (PKR) plays a major role in the innate immune response in humans. PKR binds dsRNA non-sequence specifically and requires a minimum of 15 bp dsRNA for one protein to bind and 30 bp dsRNA to induce protein dimerization and activation by autophos...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Heinicke, Laurie A., Wong, C. Jason, Lary, Jeffrey, Nallagatla, Subba Rao, Diegelman-Parente, Amy, Zheng, Xiaofeng, Cole, James L., Bevilacqua, Philip C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763119/
https://ncbi.nlm.nih.gov/pubmed/19445956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.05.005
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