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Nosiheptide Biosynthesis Featuring a Unique Indole Side Ring Formation on the Characteristic Thiopeptide Framework

Nosiheptide (NOS), belonging to the e series of thiopeptide antibiotics that exhibit potent activity against various bacterial pathogens, bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Here, cloning, sequencing and characterization of...

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Autores principales: Yu, Yi, Duan, Lian, Zhang, Qi, Liao, Rijing, Ding, Ying, Pan, Haixue, Wendt-Pienkowski, Evelyn, Tang, Gongli, Shen, Ben, Liu, Wen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763056/
https://ncbi.nlm.nih.gov/pubmed/19678698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900133x
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