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Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
The optimization of a Ugi reaction involving the mixing of furfurylamine, benzaldehyde, boc-glycine and t-butylisocyanide is described. Triplicate runs of 48 parallel experiments are reported, varying concentration, solvent and the excess of some of the reagents. The isolation of the product was ach...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
MyJove Corporation
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762777/ https://ncbi.nlm.nih.gov/pubmed/19066532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/942 |
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