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Development of a Merged Conjugate Addition/Oxidative Coupling Sequence. Application to the Enantioselective Total Synthesis of Metacycloprodigiosin and Prodigiosin R1

A merged conjugate addition/oxidative coupling sequence that represents an efficient strategy for preparing structurally diverse pyrroles has been developed. Success of the method hinged upon the controlled oxidative coupling of unsymmetrical silyl bis-enol ether intermediates, formed by the 1,4-add...

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Detalhes bibliográficos
Main Authors: Clift, Michael D., Thomson, Regan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762730/
https://ncbi.nlm.nih.gov/pubmed/19754115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja906122g
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