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Enantioselective Total Synthesis and Confirmation of the Absolute and Relative Stereochemistry of Streptorubin B

The enantioselective total synthesis of the pyrrolophane natural product streptorubin B is described. Key steps in the concise route include application of a one-pot enantioselective aldol cyclization/Wittig reaction and an anionic oxy-Cope rearrangement to forge the crucial 10-membered ring. Compar...

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Detalhes bibliográficos
Main Authors: Hu, Dennis X., Clift, Michael D., Lazarski, Kiel E., Thomson, Regan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073088/
https://ncbi.nlm.nih.gov/pubmed/21166419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja109165f
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