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9,10-Anthraquinone hinders β-aggregation: How does a small molecule interfere with Aβ-peptide amyloid fibrillation?

Amyloid aggregation is linked to a number of neurodegenerative syndromes, the most prevalent one being Alzheimer's disease. In this pathology, the β-amyloid peptides (Aβ) aggregate into oligomers, protofibrils, and fibrils and eventually into plaques, which constitute the characteristic hallmar...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Convertino, Marino, Pellarin, Riccardo, Catto, Marco, Carotti, Angelo, Caflisch, Amedeo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley Subscription Services, Inc., A Wiley Company 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762591/
https://ncbi.nlm.nih.gov/pubmed/19309732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.87
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