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Disordered Binding of Small Molecules to Aβ(12–28)

In recent years, an increasing number of small molecules and short peptides have been identified that interfere with aggregation and/or oligomerization of the Alzheimer β-amyloid peptide (Aβ). Many of them possess aromatic moieties, suggesting a dominant role for those in interacting with Aβ along v...

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Autori principali: Convertino, Marino, Vitalis, Andreas, Caflisch, Amedeo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308868/
https://ncbi.nlm.nih.gov/pubmed/21969380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.285957
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