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Organism complexity anti-correlates with proteomic β-aggregation propensity

We introduce a novel approach to estimate differences in the β-aggregation potential of eukaryotic proteomes. The approach is based on a statistical analysis of the β-aggregation propensity of polypeptide segments, which is calculated by an equation derived from first principles using the physicoche...

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Bibliografiska uppgifter
Huvudupphovsmän: Tartaglia, Gian Gaetano, Pellarin, Riccardo, Cavalli, Andrea, Caflisch, Amedeo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253303/
https://ncbi.nlm.nih.gov/pubmed/16155201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051473805
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