Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Novel Therapeutic Target

Multiple Myeloma (MM) remains incurable despite novel therapies, suggesting the need for further identification of factors mediating tumorigenesis and drug resistance. Using both in vitro and in vivo MM xenograft models, we show that plasmacytoid dendritic cells (pDCs) in the bone marrow (BM) microe...

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Autori principali: Chauhan, Dharminder, Singh, Ajita V., Brahmandam, Mohan, Carrasco, Ruben, Bandi, Madhavi, Hideshima, Teru, Bianchi, Giada, Podar, Klaus, Tai, Yu-Tzu, Mitsiades, Constantine, Raje, Noopur, Jaye, David L., Kumar, Shaji K, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762396/
https://ncbi.nlm.nih.gov/pubmed/19800576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.08.019
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