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Inhibition of Early Endosome Fusion by RAB5 - Binding Defective RAS Interference 1 Mutants

Rin1 has been shown to play an important role in endocytosis. In this study we demonstrated that depletion of Rin1 from the cytosol blocked the fusion reaction. More importantly, endosome fusion was rescued by the addition of Rin1 proteins depending on the presence of Rab5, and its effector EEA1. Fu...

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Detalhes bibliográficos
Main Authors: Galvis, Adriana, Balmaceda, Valeria, Giambini, Hugo, Conde, Alejandro, Villasana, Zoilmar, Fornes, Miguel W., Barbieri, M. Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761816/
https://ncbi.nlm.nih.gov/pubmed/19032933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.11.009
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