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FUNCTIONAL DETERMINANTS OF RAS INTERFERENCE 1 MUTANTS REQUIRED FOR THEIR INHBITORY ACTIVITY ON ENDOCYTOSIS
In this study, we initiated experiments to address the structure-function relationship of Rin1. A total of ten substitute mutations were created, and their effects on Rin1 function were examined. Of the ten mutants, four of them (P541A, E574A, Y577F, T580A) were defective in Rab5 binding, while two...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257578/ https://ncbi.nlm.nih.gov/pubmed/19118546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.12.003 |
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