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Functional complementation of RNA interference mutants in trypanosomes

BACKGROUND: In many eukaryotic cells, double-stranded RNA (dsRNA) triggers RNA interference (RNAi), the specific degradation of RNA of homologous sequence. RNAi is now a major tool for reverse-genetics projects, including large-scale high-throughput screens. Recent reports have questioned the specif...

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Detalhes bibliográficos
Main Authors: Rusconi, Filippo, Durand-Dubief, Mickaël, Bastin, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549545/
https://ncbi.nlm.nih.gov/pubmed/15703078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-5-6
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