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Inhibition of Early Endosome Fusion by RAB5 - Binding Defective RAS Interference 1 Mutants

Rin1 has been shown to play an important role in endocytosis. In this study we demonstrated that depletion of Rin1 from the cytosol blocked the fusion reaction. More importantly, endosome fusion was rescued by the addition of Rin1 proteins depending on the presence of Rab5, and its effector EEA1. Fu...

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Bibliografische gegevens
Hoofdauteurs: Galvis, Adriana, Balmaceda, Valeria, Giambini, Hugo, Conde, Alejandro, Villasana, Zoilmar, Fornes, Miguel W., Barbieri, M. Alejandro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761816/
https://ncbi.nlm.nih.gov/pubmed/19032933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.11.009
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