Association of Sequence Variations in Vitamin K Epoxide Reductase and γ-Glutamyl Carboxylase Genes with Biochemical Measures of Vitamin K Status

Genetic factors, specifically the VKORC1 and GGCX genes, have been shown to contribute to the interindividual variability in response to the vitamin K-antagonist, warfarin, which influences the dose required to achieve the desired anticoagulation response. These differences in warfarin sensitivity m...

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Bibliographic Details
Main Authors: Crosier, Michael D., Peter, Inga, Booth, Sarah L., Bennett, Grace, Dawson-Hughes, Bess, Ordovas, Jose M.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761647/
https://ncbi.nlm.nih.gov/pubmed/19436136
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