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Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

microRNA-155 (miR-155) has been implicated as a central regulator of the immune system, but its function during acute inflammatory responses is still poorly understood. Here we show that exposure of cultured macrophages and mice to lipopolysaccharide (LPS) leads to up-regulation of miR-155 and that...

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Detalhes bibliográficos
Main Authors: Worm, Jesper, Stenvang, Jan, Petri, Andreas, Frederiksen, Klaus Stensgaard, Obad, Susanna, Elmén, Joacim, Hedtjärn, Maj, Straarup, Ellen Marie, Hansen, Jens Bo, Kauppinen, Sakari
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761263/
https://ncbi.nlm.nih.gov/pubmed/19596814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp577
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