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Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression

Medulloblastoma (MB), originating in the cerebellum, is the most common malignant brain tumor in children. MB consists of four major groups where constitutive activation of the Sonic Hedgehog (SHH) signaling pathway is a hallmark of one group. Mouse and human SHH MBs exhibit increased expression of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Murphy, Brian L., Obad, Susanna, Bihannic, Laure, Ayrault, Olivier, Zindy, Frederique, Kauppinen, Sakari, Roussel, Martine F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857104/
https://ncbi.nlm.nih.gov/pubmed/24145352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0927
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