Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice

MicroRNAs (miRNAs) have been implicated in B cell lineage commitment, regulation of T cell differentiation, TCR signalling, regulation of IFN signalling, and numerous other immunological processes. However, their function in autoimmunity, and specifically in systemic lupus erythematosus (SLE), remai...

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Autors principals: Garchow, Barry G, Bartulos Encinas, Oscar, Leung, Yiu Tak, Tsao, Patricia Y, Eisenberg, Robert A, Caricchio, Roberto, Obad, Susanna, Petri, Andreas, Kauppinen, Sakari, Kiriakidou, Marianthi
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258486/
https://ncbi.nlm.nih.gov/pubmed/21882343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100171
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