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Mutational Inactivation of PTPRD in Glioblastoma Multiforme and Malignant Melanoma

An additional tumor suppressor gene on chromosome 9p telomeric to the CDKN2A/B locus has long been postulated to exist. Using Affymetrix 250K single nucleotide polymorphism arrays to screen for copy number changes in glioblastoma multiforme (GBM), we detected a high frequency of deletions of the PTP...

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Detalhes bibliográficos
Main Authors: Solomon, David A., Kim, Jung-Sik, Cronin, Julia C., Sibenaller, Zita, Ryken, Timothy, Rosenberg, Steven A., Ressom, Habtom, Jean, Walter, Bigner, Darell, Yan, Hai, Samuels, Yardena, Waldman, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760967/
https://ncbi.nlm.nih.gov/pubmed/19074898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3272
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