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Identification of p18(INK4c) as a Tumor Suppressor Gene in Glioblastoma Multiforme

Genomic alterations leading to aberrant activation of cyclin/cyclin-dependent kinase (cdk) complexes drive the pathogenesis of many common human tumor types. In the case of glioblastoma multiforme (GBM), these alterations are most commonly due to homozygous deletion of p16(INK4a) and less commonly d...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Solomon, David A., Kim, Jung-Sik, Jenkins, Sultan, Ressom, Habtom, Huang, Michael, Coppa, Nicholas, Mabanta, Lauren, Bigner, Darell, Yan, Hai, Jean, Walter, Waldman, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394609/
https://ncbi.nlm.nih.gov/pubmed/18381405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6388
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