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Conspirators in a Capital Crime: Co-deletion of p18(INK4c) and p16(INK4a)/p14(ARF)/p15(INK4b) in Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is one of the most dreaded cancer diagnoses due to its poor prognosis and the limited treatment options. Homozygous deletion of the p16(INK4a)/p14(ARF)/p15(INK4b) locus is among the most common genetic alterations in GBM. Two recent studies have shown that deletion and...

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Hlavní autoři: Solomon, David A., Kim, Jung-Sik, Jean, Walter, Waldman, Todd
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828676/
https://ncbi.nlm.nih.gov/pubmed/18974105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2084
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