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Mutational and Functional Analysis of the Tumor-Suppressor PTPRD in Human Melanoma
Protein tyrosine phosphatases (PTPs) tightly regulate tyrosine phosphorylation essential for cell growth, adhesion, migration, and survival. We performed a mutational analysis of the PTP gene family in cutaneous metastatic melanoma and identified 23 phosphatase genes harboring somatic mutations. Amo...
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| Publicado en: | Hum Mutat |
|---|---|
| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394620/ https://ncbi.nlm.nih.gov/pubmed/25113440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22630 |
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