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Identification of CDK2 substrates in human cell lysates

BACKGROUND: Protein phosphorylation regulates a multitude of biological processes. However, the large number of protein kinases and their substrates generates an enormously complex phosphoproteome. The cyclin-dependent kinases - the CDKs - comprise a class of enzymes that regulate cell cycle progres...

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Detalhes bibliográficos
Main Authors: Chi, Yong, Welcker, Markus, Hizli, Asli A, Posakony, Jeffrey J, Aebersold, Ruedi, Clurman, Bruce E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760876/
https://ncbi.nlm.nih.gov/pubmed/18847512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-10-r149
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