Tools for simulating evolution of aligned genomic regions with integrated parameter estimation

Controlled simulations of genome evolution are useful for benchmarking tools. However, many simulators lack extensibility and cannot measure parameters directly from data. These issues are addressed by three new open-source programs: GSIMULATOR (for neutrally evolving DNA), SIMGRAM (for generic stru...

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Bibliographic Details
Main Authors: Varadarajan, Avinash, Bradley, Robert K, Holmes, Ian H
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Software
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760874/
https://ncbi.nlm.nih.gov/pubmed/18840304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-10-r147
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