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Tools for simulating evolution of aligned genomic regions with integrated parameter estimation

Controlled simulations of genome evolution are useful for benchmarking tools. However, many simulators lack extensibility and cannot measure parameters directly from data. These issues are addressed by three new open-source programs: GSIMULATOR (for neutrally evolving DNA), SIMGRAM (for generic stru...

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Bibliografiske detaljer
Main Authors: Varadarajan, Avinash, Bradley, Robert K, Holmes, Ian H
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760874/
https://ncbi.nlm.nih.gov/pubmed/18840304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-10-r147
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