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Tools for simulating evolution of aligned genomic regions with integrated parameter estimation

Controlled simulations of genome evolution are useful for benchmarking tools. However, many simulators lack extensibility and cannot measure parameters directly from data. These issues are addressed by three new open-source programs: GSIMULATOR (for neutrally evolving DNA), SIMGRAM (for generic stru...

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Detalhes bibliográficos
Main Authors: Varadarajan, Avinash, Bradley, Robert K, Holmes, Ian H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760874/
https://ncbi.nlm.nih.gov/pubmed/18840304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-10-r147
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