AMPKα2 deficiency exacerbates pressure-overload induced left ventricular hypertrophy and dysfunction in mice

AMP activated protein kinase (AMPK) plays an important role in regulating myocardial metabolism and protein synthesis. Activation of AMPK attenuates hypertrophy in cultured cardiac myocytes, but the role of AMPK in regulating the development of myocardial hypertrophy in response to chronic pressure...

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Bibliographic Details
Main Authors: Zhang, Ping, Hu, Xinli, Xu, Xin, Fassett, John, Zhu, Guangshuo, Viollet, Benoit, Xu, Wayne, Wiczer, Brian, Bernlohr, David A., Bache, Robert J., Chen, Yingjie
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760829/
https://ncbi.nlm.nih.gov/pubmed/18838626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.114702
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