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First-principles study of non-heme Fe(II) halogenase SyrB2 reactivity

We present here a computational study of reactions at a model complex of the SyrB2 enzyme active site. SyrB2, which chlorinates L-threonine in the syringomycin biosynthetic pathway, belongs to a recently discovered class of α-ketoglutarate (αKG), non-heme Fe(II) dependent halogenases that shares man...

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Bibliografiset tiedot
Päätekijät: Kulik, Heather J., Blasiak, Leah C., Marzari, Nicola, Drennan, Catherine L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760000/
https://ncbi.nlm.nih.gov/pubmed/19807187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja905206k
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