A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40(phox) and selective defects in neutrophil NADPH oxidase activity

Chronic granulomatous disease (CGD), an immunodeficiency with recurrent pyogenic infections and granulomatous inflammation, results from loss of phagocyte superoxide production by recessive mutations in any 1 of 4 genes encoding subunits of the phagocyte NADPH oxidase. These include gp91(phox) and p...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Matute, Juan D., Arias, Andres A., Wright, Nicola A. M., Wrobel, Iwona, Waterhouse, Christopher C. M., Li, Xing Jun, Marchal, Christophe C., Stull, Natalie D., Lewis, David B., Steele, MacGregor, Kellner, James D., Yu, Weiming, Meroueh, Samy O., Nauseef, William M., Dinauer, Mary C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2009
Materias:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759653/
https://ncbi.nlm.nih.gov/pubmed/19692703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231498
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares