The preferentially expressed antigen in melanoma (PRAME) inhibits myeloid differentiation in normal hematopoietic and leukemic progenitor cells

The preferentially expressed antigen in melanoma (PRAME) is expressed in several hematologic malignancies, but either is not expressed or is expressed at only low levels in normal hematopoietic cells, making it a target for cancer therapy. PRAME is a tumor-associated antigen and has been described a...

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Opis bibliograficzny
Główni autorzy: Oehler, Vivian G., Guthrie, Katherine A., Cummings, Carrie L., Sabo, Kathleen, Wood, Brent L., Gooley, Ted, Yang, Taimei, Epping, Mirjam T., Shou, Yaping, Pogosova-Agadjanyan, Era, Ladne, Paula, Stirewalt, Derek L., Abkowitz, Janis L., Radich, Jerald P.
Format: Artigo
Język:Inglês
Wydane: American Society of Hematology 2009
Hasła przedmiotowe:
Myeloid Neoplasia
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759652/
https://ncbi.nlm.nih.gov/pubmed/19625708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-170282
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