The preferentially expressed antigen in melanoma (PRAME) inhibits myeloid differentiation in normal hematopoietic and leukemic progenitor cells

The preferentially expressed antigen in melanoma (PRAME) is expressed in several hematologic malignancies, but either is not expressed or is expressed at only low levels in normal hematopoietic cells, making it a target for cancer therapy. PRAME is a tumor-associated antigen and has been described a...

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Bibliographic Details
Main Authors: Oehler, Vivian G., Guthrie, Katherine A., Cummings, Carrie L., Sabo, Kathleen, Wood, Brent L., Gooley, Ted, Yang, Taimei, Epping, Mirjam T., Shou, Yaping, Pogosova-Agadjanyan, Era, Ladne, Paula, Stirewalt, Derek L., Abkowitz, Janis L., Radich, Jerald P.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2009
Subjects:
Myeloid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759652/
https://ncbi.nlm.nih.gov/pubmed/19625708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-170282
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