Size of FLT3 internal tandem duplication has prognostic significance in patients with acute myeloid leukemia

FLT3 internal tandem duplications (FLT3/ITDs) in the juxtamembrane domain are found in approximately 25% of acute myeloid leukemia (AML) patients, ranging in size from 3 to hundreds of nucleotides. We examined whether the sizes of FLT3/ITDs were associated with clinical outcomes in 151 AML patients...

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Detalhes bibliográficos
Main Authors: Stirewalt, Derek L., Kopecky, Kenneth J., Meshinchi, Soheil, Engel, Julia H., Pogosova-Agadjanyan, Era L., Linsley, Jeremy, Slovak, Marilyn L., Willman, Cheryl L., Radich, Jerald P.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895777/
https://ncbi.nlm.nih.gov/pubmed/16368883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3453
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