Prognostic Significance of NPM1 Mutations in the Absence of FLT3–Internal Tandem Duplication in Older Patients With Acute Myeloid Leukemia: A SWOG and UK National Cancer Research Institute/Medical Research Council Report

PURPOSE: Younger patients with acute myeloid leukemia (AML) harboring NPM1 mutations without FLT3–internal tandem duplications (ITDs; NPM1-positive/FLT3-ITD–negative genotype) are classified as better risk; however, it remains uncertain whether this favorable classification can be applied to older p...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Ostronoff, Fabiana, Othus, Megan, Lazenby, Michelle, Estey, Elihu, Appelbaum, Frederick R., Evans, Anna, Godwin, John, Gilkes, Amanda, Kopecky, Kenneth J., Burnett, Alan, List, Alan F., Fang, Min, Oehler, Vivian G., Petersdorf, Stephen H., Pogosova-Agadjanyan, Era L., Radich, Jerald P., Willman, Cheryl L., Meshinchi, Soheil, Stirewalt, Derek L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2015
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372852/
https://ncbi.nlm.nih.gov/pubmed/25713434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.58.0571
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